After using ext4 for yyyeeeaaaarrrrrsss, when I upgraded my MX21 to MX23 I used btrfs, with subvolumes, especially for easy backup/snapshot/timeshift.
Just at install, super easy, create a small ext4 boot partition on the SSD, then a big LUKS partition, format with btrfs, create subvolumes for / /home /var /swap and that's it. No hassle with sizing correctly.
btrfs seems pretty stable. I see no diff in performance compared to ext4 because my application are not that dependant to FS speed, and with SSD anyway?
oh yeah, built-in compression too!